Latest Research: 4 Gut and Brain Health Benefits of Probiotics

Do you live in Ottawa? Are you wondering about the gut and brain health benefits of probiotics?

If so, you are in the right place.

Today, I will talk about the four benefits of probiotics for gut and brain health.

Even better, once we have explored probiotics’ gut and brain health benefits, I will explain how to choose a good probiotic.

Let’s begin by reviewing the latest research showing that probiotics can help with small intestinal bacterial overgrowth (SIBO), fungal overgrowth (SIFO), and parasites in the gut.

Probiotics Help SIBO, SIFO and Parasites In The Gut

A 2017 meta-analysis and systematic review found that probiotic therapy achieved a 53% clearance of SIBO.

A 2013 randomized controlled trial found that the probiotic Saccharomyces boulardii was as effective as the anti-fungal medication Nyastatin in treating fungal overgrowth in the gut.

A 2006 controlled clinical trial found that the probiotic Saccharomyces boulardii plus antibiotic therapy was more effective than antibiotics alone in treating Giardia lamblia parasite infection.

Let’s look at the latest research showing that probiotics can help with leaky gut.

Probiotics Help Leaky Gut

The small intestine is 20 feet long, and the lining is one cell thick.

This thin wall allows easy absorption of calories and nutrients, but it also makes it easily prone to dysfunction, such as leaky gut.

The lining’s vulnerability is why 70% of the body’s immune system resides in the small intestine.

So, if anything gets through the lining, such as food proteins or endotoxins (LPS), there is protection.

A 2023 meta-analysis and systematic review showed that probiotics help eliminate dysbiosis in the small intestine, reducing inflammation and leaky gut.

Let’s now look at the brain health benefits of probiotics.

Brain Health Benefits of Probiotics

Because of the gut-brain connection, it is no surprise that we see improvements in the brain as we improve gut health.

Inflammation in the gut leads to a build-up of toxins, which make their way into the bloodstream, crossing the blood-brain barrier and stimulating an inflammatory response.

Inflammation in the brain will then lead to cognitive and mood symptoms.

Another organ in the body that can affect brain health is the liver.

In a condition known as hepatic encephalopathy, where the liver cannot adequately clean toxins, they build up in the blood and travel to the brain, creating inflammation and symptoms.

A 2017 study concluded that probiotics probably improve recovery and may lead to improvements in the development of overt hepatic encephalopathy and brain symptoms.

Furthermore, a 2020 systematic review and meta-analysis found brain health benefits of probiotics, including the following:

• Alzheimer’s
• Aging
• Diabetes
• MCI
• Depression

Let’s look at how probiotics improve brain health by helping the Limbic system and stress response.

Brain Health Health Benefits of Probiotics By Helping The Limbic System And Stress Response

The brain’s Limbic system includes the Thalamus, Hippocampus, Hypothalamus and Amygdala.

The Limbic system has two tracts.

Firstly, the neuro-endocrine tract includes the thalamus and hypothalamus.

In this tract, when you see a stressful event like a car accident, the Thalamus and Hypothalamus stimulate the release of stress hormones such as cortisol.

Secondly, the Hippocampus and Amygdala tract.

The Hippocampus governs learning and long-term memory.

The Amygdala governs “learning through fear.”

For example, if you do something scary or unpleasant, this is where the Amygdala tags events.

A 2017 randomized control trial showed that MRI imaging showed reduced activity in the amygdala when people with IBS were treated with probiotics.

Furthermore, the researchers found improvements in depression and IBS symptoms.

Another 2023 randomized control trial found that probiotics reduced Hippocampus activation and depressive symptoms.

Interestingly, increased activation of the Hippocampus is linked to depression.

Now that we can see the benefits of probiotics for gut and brain health, let’s look at how to choose a good probiotic.

How To Choose A Good Probiotic

Choosing a probiotic can be confusing for a health consumer due to the dizzying array of choices and the manufacturers’ health benefit claims.

Let’s simplify things by looking at the three main categories of probiotics.

The three categories of probiotics include the following:

• Saccharomyces Bourlardii
• A blend of Lactobacillus and Bifidobacterium
• Bacillus strains (Soiled based probiotics)

Most of the studies highlighted above are high-level meta-analysis papers that summarize clinical trials.

Each clinical trial uses different formulas of probiotics, but all of them show positive health benefits.

This tells us that it does not matter what probiotics you use; they all will be potentially helpful.

What you should consider when choosing which probiotics to use are three main criteria, including the following:

1. The probiotics should be made by a company that follows approved manufacturing practices.
2. Third-party independent testing to ensure reliability.
3. The probiotics are free of fillers, irritants and common allergens such as wheat, dairy, corn and soy.

Finally, let’s look at how much and for how long you should take probiotics.

Based on clinical evidence, the following chart shows the optimum dosing and duration for the three probiotic categories.

If you want to self-prescribe a probiotic, choose any of the above categories and start taking them.

Choose a different category if you do not see any benefit after 2-3 weeks.

If you initially experience some digestive upset for more than 2-3 days, stop and move on to another category.

You should take them for three months to benefit most from all three categories.

I use muscle response testing to determine which probiotic(s) are most beneficial in my practice.

Now It’s Over To You

Are you considering taking probiotics to improve your gut or brain health?

Leave me a comment below.

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If you need help, I suggest you book a free functional medicine discovery session with me to determine whether my functional medicine approach fits your child’s needs.

Disclaimer

The information provided on this website is for educational purposes only and is not intended to diagnose or treat any disease. Please do not apply this information without first speaking with your doctor.